The RESTORE Project is built upon constructive discussions between orthopaedic surgeons, tissue-engineers, material scientists, cell biologists, small and medium-sized enterprises (SMEs) to co-design an effective approach to manage the specific unmet clinical needs to treat knee chondral lesions. Ten partners from seven countries (Portugal, Spain, Italy, Germany, Sweden, Norway, Iceland and Finland), including Research and Technological Development institutes and two small-medium sized enterprises.